Mass Spectrometry Laboratory

We are currently equipped with
three state-of-the art LC-MS systems.

All Gundry lab members have hands-on access to the instrumentation. Students and post-docs should expect to become proficient in their use.

Moon

(Keith Moon)

Thermo Scientific Orbitrap Eclipse Tribrid with ETD and FAIMS Pro interface — Thermo Scientific Orbitrap Eclipse Tribrid
with ETD and FAIMS Pro interface

Moon is generally used for our glycomics and intact glycopeptide analyses. Occasionally we also use it for top-down.

Simone

(Nina Simone)

Thermo Scientific Orbitrap Exploris 480 with FAIMS Pro interface and Easy IC — Thermo Scientific Orbitrap Exploris 480
with FAIMS Pro interface and Easy IC

Simone is dedicated to our cell surface proteomics experiments.

Marley

(Bob Marley)

Thermo Scientific Orbitrap Exploris 480
with Biopharma Option and Easy IC

Marley is used for targeted and untargeted quantification of complex proteomics samples.

Automated sample handling is key for our advanced sample preparation workflows for low-input, reproducible proteomics and glycomics. These robotic platforms are used for sample digestion, solid phase extraction, magnetic-bead based enrichments, and desalting.